http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2715891-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25a6289b957369e15597b9b73392417e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13c71cca58dd0d7d72dc74436cda6220 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3ada8ccfbe79913b5a980ac83fbaa51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff8ba24e0517a69737169152294095fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb19a0e8e5d1bfa3d41b0132e002523c |
| publicationDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2715891-C1 |
| titleOfInvention | Method for simulation of tumor growth dynamics in experiment |
| abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine and can be used for simulation of tumor growth dynamics in experiment. Method for simulation of tumor growth dynamics in experiment involves systemic change of thyroid status in white outbred rats weighing 200–250 g. For this purpose 0.5 ml of a suspension of tumor cell of ovarian cancer containing not less than 1×10tumor cells is intraperitoneally injected. That is followed by accelerating tumor growth by inducing drug hyperthyroidism by administering L-thyroxine 100±20 mcg per 100 g of animal's body weight once a day, tumor growth inhibition is ensured by induction of drug hypothyroidism by administering propylthiouracil 2.0±0.20 mg per 100 g of animal's body once a day. Substances are administered intragastrically through a non-traumatic metal probe daily starting 3 days before the tumor cells inoculation. Further, tumor growth dynamics and life span of tumor carrier animals are evaluated.EFFECT: using the given method enables assessing tumor growth dynamics in an experiment based on the animal's survival depending on the induced thyroid status.1 cl, 1 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2743219-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2743219-C9 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2794641-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2779358-C1 |
| priorityDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.