http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2711655-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5421b664c7c22ec24417a9e81faa650 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-263 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-263 |
| filingDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1306bda4b0dc3ff292823f406b038ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7f3c40fd3a6dbe0d7d254c3e429469d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c11e09c07ba33dd55a41492262f0ff16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1131e5763061d1de89b82bd7d3a9271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be576115cccfb6d9844cf5f603aaffee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d81af9c38e65f2b9949d66a30a04a97a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae52799ae2ca7fd4752be100fe06677 |
| publicationDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2711655-C1 |
| titleOfInvention | Method for large-scale synthesis of potassium salt of 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamido]ethane sulphonic acid |
| abstract | FIELD: chemistry.SUBSTANCE: invention relates to a method for large-scale synthesis of potassium salt of 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamido]ethane sulphonic acid. Method comprises the following stages: a) alkylation of 4-phenylpyrrolidinone-2 to obtain ethyl ester of 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetic acid; b) hydrolysis of ethyl ether of 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetic acid to obtain free acid; c) reacting 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetic acid with N-hydroxysuccinimide to obtain N-hydroxysuccinimide ester of 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetic acid; and d) reacting 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetic acid N-hydroxysuccinimide ester with 2-aminoethanesulphonic acid and potassium hydroxide to obtain potassium salt 2-[2-(2-oxo-4-phenylpyrrolidine -1-yl)acetamido]ethanesulphonic acid.EFFECT: disclosed method enables to carry out large-scale synthesis of the end product.1 cl, 4 ex |
| priorityDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.