http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2711545-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99cd2888b2026702c522c60b1544ff90 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e6e7040baebd8ae922f1d10d572d5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3d1e1b414313036308f9ddbd86484cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_206611e3a440a60af694eb6cd68c4c84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bb1da867ac0e9f39a76b267963ba745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17b384c2786d60df8dc57a96483ae9f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbcefbf4ab96406ad602b0242f429bd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47fd6d051885b2939526608d6e7d78b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c46be2df3c0570d5f3b3dd3e0c61007f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c69690428c300b057f81d5582e215fa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f978ade97047356cfb4a62ed3ed95ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf620b17e7ce469ccb3dff61be40e599 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8168a51c59fd70bc4bbf8d3187bcd6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_530ddb379548e094d21c489eb4c2d1b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92ba9a330dee5bbb0d8bf24d06e6b923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_681131b7dc575b15d3e525e8c69e1bb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb53d35774740a76ba3258e5042d624f |
| publicationDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2711545-C1 |
| titleOfInvention | Method for producing a bioresorbed tube based on methacrylized gelatine and methacrylized fibroin and a method for increasing the consistency of intestinal anastomosis using such a tube |
| abstract | FIELD: biotechnology. n SUBSTANCE: invention relates to biotechnology and medicine. In more detail, the invention refers to surgery, namely to methods for reducing the incidence of intestinal anastomosis. Invention relates to a method of producing a bioresorbable tube based on methacrylized gelatine and methacrylized fibroin, involving the following steps: a) dissolving in hexafluoroisopropanol of macromonomers: methacrylized gelatine (GMA) at rate of 10 wt% and methacrylized fibroin (FMA) in amount of 4 wt% at 55±5 °C for 18–36 hours; b) obtaining a mixture which includes equal parts of solutions of GMA and FMA and a photoinitiator of diphenyl(2,4,6-trimethylbenzoyl)phosphine in amount of 5 wt% by weight of macromonomers; c) preparing a guide for forming a tube by degreasing, followed by drying a surface of a glass rod with a circular cross-section of 2–15 cm in diameter; d) preparing the reinforcing thread by holding untwisted 8/0-4/0 silk thread in the mixture obtained in step b); e) forming the first layers of the bioresorbable tube on the guide by immersing it in the mixture obtained at step b) for 5–10 seconds with subsequent rotation and exposure of the obtained workpiece in the ultraviolet lamp light for at least 2 minutes; f) reinforcing the end sections of the tube by laying the thread in turns at distance of 2–5 mm from the ends of the formed tube to the workpiece obtained at step e); g) forming the outer layers of the bioresorbable tube by immersing the workpiece obtained at step f) into the mixture obtained at step b) for 5–10 seconds, followed by rotating and exposing the obtained tube in the ultraviolet lamp light for at least 2 minutes; h) processing the formed tube by holding in distilled water for 1–1.5 hours, followed by holding in 96 % ethanol for 12–18 hours and repeated holding in distilled water for 1–1.5 hours, treating internal surface of the formed tube with chloroform. n EFFECT: obtaining articles having a programmable rate of degradation, low immunogenicity, ease of modification; developing a new approach to solving the problem of anastomosis inconsistency, where, in addition to mechanical protection of the anastomosis area, the implant is actively built into the regeneration process. n 11 cl, 3 dwg, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115181226-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115181226-A |
| priorityDate | 2018-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.