abstract |
FIELD: chemistry.SUBSTANCE: invention relates to biochemistry, in particular to a polynucleotide encoding a stabilized multispecific antibody construct. What is also disclosed is a pharmaceutical composition containing said antibody, an expression vector containing said polynucleotide, a host cell containing said polynucleotide. Disclosed is a method of producing said antibody, as well as use of said antibody or said pharmaceutical composition for treatment.EFFECT: invention enables to obtain a stabilized multispecific antibody construct.12 cl, 3 dwg, 6 tbl, 2 ex |