abstract |
FIELD: medicine. n SUBSTANCE: group of inventions relates to medicine and concerns a medicinal agent for treating cancer, comprising a Toll-like receptor agonist and a LAG-3 protein, a variant or derivative thereof, where the Toll-like receptor agonist is Toll-like receptor 3 agonist, and the LAG-3 protein, a variant or derivative thereof is a fusion protein of LAG-3 and IgG protein. Group of inventions also relates to using a combination comprising a Toll-like receptor agonist and a LAG-3 protein, a variant or derivative thereof, for inducing a specific immune response against a cancer cell. n EFFECT: group of inventions provides reducing the tumour size and increasing the survival rate. n 11 cl, 1 ex, 26 dwg |