http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2707075-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_484543b2a4169d6d89a6874cd4d84480 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a52048a0d6a7e7c44a2d5dbc89d4dd0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8ac03ce836bc35666849276f3c3acb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd0edf7c32fad0dd33cd52f11408ed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7084841011550fb3f2c1a806203bbcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c8c6a72832cc8cdc91fbfe927aa743c |
| publicationDate | 2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2707075-C1 |
| titleOfInvention | Method for prediction of the risk of developing web-associated tumors in the patients with acute ebv-infection |
| abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to laboratory diagnostics, and can be used for prediction of developmental risk EBV-associated tumors in patients with acute EBV-infection. That is ensured by detecting peripheral blood leukocytes expressing transcription variants of mRNA receptors and components of TGFB1-associated signalling pathways: TGFB1, TGFBR1, TGFBR2, Smad2, Smad3, Smad4, PRKCB, MAP3K7, MAP3K11, MAP3K1, MAPK1, MAP2K4, MAPK8, JUN, TRAF6, IKBKG, IKBKB, CHUK, ELP1, NFKBI-α, NFKBI-β, NFKB1, RELA using a microchip with oligonucleotide probes applied on it, complementary to sequences of said mRNA. Increase of expression levels of mRNA of transcription version 1 of Smad2, transcription version 4 of IKBKG, transcription version 1 of IKBKG and total level of mRNA of NFKBI, and reduction of expression level of mRNA of transcription version 2 of PRKCB are considered as a risk factor of development EBV-associated tumors.EFFECT: invention enables to predict EBV-associated tumors at early stage of tumor transformation progression.1 cl, 3 dwg, 1 tbl, 4 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115786509-A |
| priorityDate | 2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 338.