abstract |
FIELD: medicine; pharmaceuticals.SUBSTANCE: invention relates to immunology. Disclosed is a non-competitive neuregulin (NRG) allosteric antibody against human HER3 and a fragment thereof, as well as a coding nucleic acid, a vector, a host cell, a pharmaceutical composition and a method of treating cancer.EFFECT: present invention can find further application in diagnostics and therapy.15 cl, 13 dwg, 2 tbl, 9 ex |