http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2703108-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bffcf449937800fbd7d3741df647132d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2408 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26 |
| filingDate | 2018-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43391adb52a15033153b20ba4e40d26a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c709e11d1c5ff11619cd3994f2b38c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cae00e3c81229d476cb55b62313eb66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d81f02daa0bff29eec1a4a9c91684680 |
| publicationDate | 2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2703108-C1 |
| titleOfInvention | Method of producing a pharmaceutical substance of hyaluronidase |
| abstract | FIELD: medicine; pharmaceuticals. n SUBSTANCE: invention refers to production of enzyme pharmaceutical substances, namely to a method for production of hyaluronidase from animal raw material – testes of bovine animals (cattle). Preliminarily milled animal raw material is subjected to extraction with aqueous solution of acetic acid with constant stirring in ratio of 1 to 2 for 4 hours. Then extract is centrifuged and filtered. PH is adjusted to 4.0–4.5, sorption and desorption are carried out with eluent with pH=10–11 on macroporous sulphocationite, eluate is concentrated in tangential flow and lyophilised. n EFFECT: invention increases activity of hyaluronidase. n 8 cl, 3 ex |
| priorityDate | 2018-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.