http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2702609-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fe5ceaa52027f7fc13a6ed9c12dc9e7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-32 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0786 |
| filingDate | 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b03e95a9b819d30c10fa4323d14f452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae3f170571067f646501ada1e79f397b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1729bf9c681a525cd0197337866d952 |
| publicationDate | 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2702609-C1 |
| titleOfInvention | Method for simulating tuberculosis infection in vitro |
| abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to experimental medicine, and can be used for simulating tuberculosis infection in vitro. Granuloma-like structures are obtained from mononuclear cells of venous blood in the presence of tuberculosis mycobacteria cultured in a three-dimensional matrix. Blood mononuclear cells are resuspended in blood autoplasma with adding tuberculosis mycobacteria into the obtained suspension in ratio of excitant: cell from 3:1 to 1:50, followed by addition of 10 % CaClat rate of 150 mcl per 1 ml of the cell suspension.EFFECT: method provides formation of a coagulum of a large volume and with a large number of cells and a significant expansion of the solved experimental problems by stable production of three-dimensional tuberculosis granulomas in vitro without using heterologous commercial preparations, which allows eliminating artificial effects on fine mechanisms of interaction of immune system cells in vitro.1 cl, 1 tbl, 4 ex |
| priorityDate | 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.