| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38b4359287cd465f1367c4b6ac87218e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcdccc68b866b57c974e735357a9c86b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52d03206ec173d75033efe3568b44dcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a938ed167c61cf6a04718622bdf9c9d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5624be6e43ac3b39047ad3301b462755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_075b764c6b03879ed0882b12c2d2ba30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563f3c04639363a4271099880c987a46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6037d9051f47b3c118c54d7ddbaf5951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9aab12e09765c972b87295394113eb5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cf7189e2441cd9b69e8ac0f1848407d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4541ebfa99fb7d105f97b1b0140b1299
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5329a78fadc72448e192f9ee4b11c5b1 |
| publicationDate |
2019-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2700565-C1 |
| titleOfInvention |
Method for determining predisposition to developing obesity in children in conditions of excessive contamination with aluminum |
| abstract |
FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly to paediatrics and endocrinology, and aims at determining predisposition to developing obesity in children in conditions of excessive contamination with aluminum. Blood and urine samples are taken in a child. Urine sample is used to determine content of aluminum, and blood serum – IgG level to aluminum. DNA of buccal epithelium is extracted. On the detecting amplifier using polymerase chain reaction in real time genotyping of MTNR1B (rs 10830963) and SIRT1 (rs 7069102) gene polymorphism is carried out. At simultaneous detection of the following diagnostic criteria: presence of variant homozygous or heterozygous genotypes of gene MTNR1B (rs 10830963) and gene SIRT1 (rs 7069102) under condition of simultaneous excess of aluminum concentration in urine by more than 2 times compared to reference level of aluminum content in urine, as well as when the physiological norm of IgG level to aluminum is exceeded in comparison with the upper limit, a conclusion is made on the child's propensity to develop obesity in conditions of excessive contamination with aluminum.EFFECT: invention provides reliable assessment of aluminum effect on predisposition of manifestations of endocrine disorders in the form of obesity.1 cl, 2 tbl, 2 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2771145-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2783252-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2779085-C1 |
| priorityDate |
2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |