| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ae6dd5bafbd2dd69035367385d754c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2018-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e04d927934379cac8b02479ed2d3af7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ad406839dc4b41f94576761fa2b337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d77b8f7f57fadbfa87307c7d928e7b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ce8bb6665e251b9f9c35bb90fa92e09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccfdb80b9264113cb6ebc91d3009acfd |
| publicationDate |
2019-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2699558-C2 |
| titleOfInvention |
Agent for targeted therapy of malignant growths |
| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to 1-isobutanoyl-2-isopropyl isothiourea dichloroacetate (compound T1084) with the structural formula: n n n n as a target therapeutic agent for solid malignant growths, having a complex anti-non-regional action – NOS-inhibiting anti-angiogenic and PDK1-inhibiting hypoxia-oriented cytotoxic. n EFFECT: providing effective and stable anti-tumor action and inhibiting (or inhibiting) development of tumor resistance to anti-angiogenic therapy, as well as broader capabilities for developing new pharmacological agents for complex targeted therapy of oncological diseases. n 5 cl, 1 dwg, 3 tbl, 5 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2804771-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2733883-C2 |
| priorityDate |
2018-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |