Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b460ef7cc6975d575dc038bbbca8cf3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f70622786aa193684274f122b2e873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_888283a8088a59aaa888f45cf882da5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74c5167d2c9eae9effa3bc202d136ba6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_622a2683a31c6c54b91671fd8a639f85 |
publicationDate |
2022-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2698727-C9 |
titleOfInvention |
Covalent linkers in antibody-drug conjugates, methods for preparing them and use thereof |
abstract |
FIELD: medicine. n SUBSTANCE: group of inventions refers to medicine and concerns a linker-active agent for preparing an antibody-drug conjugate containing a compound of formula I or its pharmaceutically acceptable salt. Group of inventions also relates to a targeting moiety-drug conjugate for treating HER2-positive cancer in a subject; method of treating HER2-positive cancer in a subject involves administering a targeting moiety-drug conjugate to a subject in need of such treatment. n EFFECT: group of inventions provides reduced rate of decomposition of the anticancer conjugate compared to known conjugates. n 13 cl, 3 ex, 7 dwg, 4 tbl |
priorityDate |
2015-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |