| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9008466a40998f8be8e54cd3aceb10a2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M16-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 |
| filingDate |
2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a500b69849cf4e070f7443d33403b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf18d31e3b626414080bc578f76a961
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_768632123315480ebd5a7524cbbe5ffa |
| publicationDate |
2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2697867-C2 |
| titleOfInvention |
Inhalation particles containing combination of anticholinergic, corticosteroid and beta-adrenergic agents |
| abstract |
FIELD: chemistry; medicine.SUBSTANCE: present invention relates to multicomponent microparticles for use in a composition for preventing and/or treating inflammatory or obstructive respiratory diseases. Each microparticle contains a combination of beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide as active ingredients at ratio of 35:10:55 to 94:1:5 by weight. Method of producing said microparticles involves preparing a solution of three said active components in a solvent consisting of a mixture of ethanol and water in ratio of 85:15 to 95:5 by volume, forming an aerosol from the obtained solution and drying the sprayed droplets to form microparticles. Obtained microparticles are characterized by a shape factor from 0.95 to 1.05. Also described are a pharmaceutical aerosol composition for metered dose inhalers containing said microparticles in a suspension in a liquefied propellant gas, and a dry powder composition containing said microparticles and a carrier which is an alpha-lactose monohydrate in combination with magnesium stearate. Also described are a metered inhaler under pressure and a dry powder inhaler containing said pharmaceutical composition.EFFECT: microparticles according to the invention are characterized by homogeneous morphology and are stable for a long period of time.12 cl, 1 dwg, 7 tbl, 4 ex |
| priorityDate |
2014-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |