http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2692247-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ae6dd5bafbd2dd69035367385d754c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9950fba02c3820c54a50408623fcb2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60dae8bfb4cf3121afc4e853e4451dd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d770424b566079522d4a062d7bb9c4e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0647ca34d86c906e81e069e6b2491f83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e61125c79fcaad3bd02721b277f187f |
| publicationDate | 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2692247-C1 |
| titleOfInvention | Method of postoperative delirium treatment |
| abstract | FIELD: medicine. n SUBSTANCE: invention refers to medicine, namely to a method of treating postoperative delirium including intravenous dexmedetomidine in the early postoperative period under control of sedation. That is ensured by immediate initiation of an intensive therapy following diagnosing postoperative delirium in two-step combined monitoring of sedation and delirium, wherein at the first step, assessing agitation – sedation with the help of a Richmond score (RASS) score and in the case of an estimate of -3 to +5 points, a transition to a second step is performed – delta estimation based on a CAM-ICU scale, then dexmedetomidine is introduced in microfluid for 24 hours in dose of 0.8 mcg/kg/h, thereafter, the patient is brought into a diagnostic window, wherein in case of acute change of mental status or fluctuation thereof combined with inattentiveness or disorganized thinking, or a violation of the level of consciousness, the dexmedetomidine is administered again for 24 hours in dose of 0.8 mcg/kg/h, then the dexmedetomidine infusion is deactivated with the following assessment of the patient's mental status on the CAM-ICU scale, wherein the length of treatment is determined based on the achieved results of the absence of the signs of acute disturbances of mental status in the patient in accordance with the above diagnostic algorithm, but not more than 8 days. n EFFECT: invention allows to reduce intensity of clinical manifestations of delirium and to reduce duration of development of delirium in postoperative patients, to increase diagnostic and therapeutic possibilities, to provide wide application of a method of delirium treatment irrespective of type of operation. n 1 cl, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2770274-C1 |
| priorityDate | 2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.