http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2691752-C1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99cd2888b2026702c522c60b1544ff90 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17b384c2786d60df8dc57a96483ae9f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8168a51c59fd70bc4bbf8d3187bcd6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e6e7040baebd8ae922f1d10d572d5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_530ddb379548e094d21c489eb4c2d1b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92ba9a330dee5bbb0d8bf24d06e6b923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3d1e1b414313036308f9ddbd86484cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f978ade97047356cfb4a62ed3ed95ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbcefbf4ab96406ad602b0242f429bd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c5ebbf13cbdf50b8190b4a5c1b8f1ab |
publicationDate | 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2691752-C1 |
titleOfInvention | Method of formation of three-dimensional bioresorbable structures |
abstract | FIELD: medicine. n SUBSTANCE: invention relates to medicine and biotechnology. Method for obtaining bioresorbable three-dimensional porous structures based on methacrylized gelatin and silk fibroin, comprising the following stages: dissolving silk fibroin in an aqueous solution of lithium bromide; freezing of an aqueous solution of silk fibroin and lyophilization; dissolving gelatin in potassium phosphate buffer and adding to the solution an excess of methacrylic anhydride; carrying out the reaction of methacrylization of gelatin; adding to the reaction mixture potassium phosphate buffer, followed by cooling and dialysis; freezing the resulting product and lyophilization; obtaining an aqueous solution of regenerated silk fibroin; obtaining a solution of methacrylated gelatin in DMSO and its cooling; adding a photoinitiator to the methacrylized gelatin solution; introducing a solution of regenerated silk fibroin into a mixture of methacrylized gelatin and a photoinitiator, followed by photopolymerization; treatment with 96 % ethyl alcohol hydrogels obtained after photopolymerization; removal of residual solvents. n EFFECT: invention provides a high photopolymerization rate, as well as the possibility of obtaining porous structures of a given shape and with a controlled structure. n 4 cl, 2 ex, 1 dwg |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154672-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115054729-A |
priorityDate | 2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.