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grantDate 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25990137ceb7646d10498a054a80455f
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publicationDate 2019-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2691620-C1
titleOfInvention Method for prediction of the risk of developing ischemic heart disease in patients with type 2 diabetes mellitus combined with subclinical thyrotoxicosis
abstract FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to cardiology, and can be used in predicting the risk of developing ischemic heart disease (IHD) in patients with type 2 diabetes mellitus combined with subclinical thyrotoxicosis. That is ensured by determining a thyrotropic hormone (TTH) level in the venous blood, calculating an intima media complex (IMC), an E/A ratio, where E is a genotype by e2/e3/e4 polymorphism of the apolipoprotein E gene, and A is a G-308 polymorphism genotype A risk index of developing ischemic heart disease is calculated in patients with type 2 diabetes mellitus with subclinical thyrotoxicosis by original calculation formula. If the IHF probability prediction factor is less than 0.89, a minimum probability of developing IHD in a patient is predicted. If coefficient is 0.90 to 0.99, a high risk of developing IHD is predicted. If the coefficient is more than 1.0, the IHD already exists.EFFECT: method provides accurate prediction of developing risk and primary prevention of ischemic heart disease in this category of patients.1 cl, 4 tbl, 3 ex
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