| abstract |
FIELD: medicine.SUBSTANCE: application of nitrosyl iron complex with N-ethylthiourea of composition [Fe(SR)(NO)]Clâ‹…[Fe(SR)Cl(NO)], where R = C(NH)(NHCH), as an antitumour agent for NO tumor therapy selected from carcinosarcoma Hs578T, invasive hormone-dependent erbb2-amplifying carcinoma of ducts of mammary gland BT-474, adenocarcinoma of human rectum Caco2 and glioblastoma A-172.EFFECT: technical result: the declared complex causes cell death of the listed tumours, wherein is nontoxic in relation to normal cells.1 cl, 9 dwg, 3 tbl |