| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
| filingDate |
2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5dca418db290b22a84b33423240e6b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_868351525660b9989b0d0daef57c5029
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40f18abf83f7f68eeb6b9d805497fe31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb62f51ede0f24fef153f769b46d4bcf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a1fbd53d5c1bab1e7d2b833d17aedd8 |
| publicationDate |
2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2687094-C2 |
| titleOfInvention |
[(s)-1-carbamoyl-2-(phenylpyrimidin-2-ylamino)ethyl]amide 2-(2-methylaminopyrimidin-4-yl)-1h-indole-5-carboxylic acid for use in treating osteoarthritis-related pain |
| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to use of [(S)-1-carbamoyl-2-(phenylpyrimidin-2-ylamino)ethyl]amide 2-(2-methylaminopyrimidin-4-yl)-1H-indole-5-carboxylic acid for treating pain associated with osteoarthritis in the knee joint, including in the patients with effusion and synovitis. Said compound is used as an active component for a pharmaceutical composition presented in the form of a single dose for intra-articular introduction. Dose for intraarticular administration ranges from 15 to 60 mg, preferably 60 mg. Invention also relates to a pharmaceutical composition for treating pain associated with osteoarthritis in the knee joint, including in patients with effusion and synovitis. n EFFECT: composition contains an effective amount of [(S)-1-carbamoyl-2-(phenylpyrimidin-2-ylamino)ethyl]amide 2-(2-methylaminopyrimidin-4-yl)-1H-indole-5-carboxylic acid as an active ingredient and pharmaceutically acceptable adjuvants. n 13 cl, 2 dwg, 3 tbl, 1 ex |
| priorityDate |
2014-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |