| abstract |
FIELD: chemistry.SUBSTANCE: invention relates to a heterocyclic imidazole compound of general formula (I), in which R is hydrogen, halogen, C-Calkoxy or C-Chalogenalkyl; one of X, Y and Z is nitrogen, and others are CH or one of X, Y and Z is CH, and others are nitrogen; M is nitrogen or CR; Ris hydrogen, oxygen, C-Calkyl or C-Chalogenalkyl. Invention also relates to a method for producing a compound of general formula (I), to use of the compound.I.EFFECT: new heterocyclic imidazole compounds of general formula (I) are produced, having inhibiting properties of poly(ADP-ribose)-polymerase (PARP).14 cl, 5 tbl, 24 ex |