| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ba2e6ab9b54dace99f1c3320ff26780 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J1-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
| filingDate |
2013-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eab0cc932d32bf6aa939de11b30fcbe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd310651dee6a831b99c42cf9c8e49f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21cae1fda7f050bbc08e55d498c086db |
| publicationDate |
2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2685956-C2 |
| titleOfInvention |
Method of purifying therapeutic proteins |
| abstract |
FIELD: biotechnology. n SUBSTANCE: disclosed is a method for reducing the level of at least one protein selected from a group consisting of plasminogen and tissue plasminogen activator in a solution containing fibrinogen. Method comprises passing human cryoprecipitate plasma containing fibrinogen through a resin for hydrophobic chromatography with charge induction in conditions, in which plasminogen and the tissue plasminogen activator binds to the resin, and recovering a cryoprecipitate solution containing fibrinogen which passes through the resin. Resin for hydrophobic chromatography with induction of molar charge is HEA or PPA resin. n EFFECT: concentration of at least one protein selected from a group consisting of plasminogen and tissue plasminogen activator in the solution is reduced by at least 50 % compared to the initial substance. n 18 cl, 8 dwg, 6 tbl, 10 ex |
| priorityDate |
2012-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |