| abstract |
FIELD: medicine; pharmaceuticals. n SUBSTANCE: pharmaceutical composition is intended for treating influenza A in a subject. Composition comprises: a) from 1 mg/ml to 20 mg/ml of compound (1) in water and b) 0.01 M to 0.1 M pharmaceutically acceptable pH modifier. Source of compound (1) is a crystalline salt of HCl compound (1) 1/2H 2 O, characterised by one or more peaks corresponding to 2-theta values measured in degrees, 10.5 ± 0.2, 5.2 ± 0.2, 7.4 ± 0.2 and 18.9 ± 0.2 on powder X-ray diffraction pattern. What is also disclosed is a method for producing a pharmaceutical composition. Each method for reducing the amount of influenza virus, inhibiting influenza virus replication and treating influenza independently uses such a pharmaceutical composition. n . n EFFECT: composition according to the invention is characterised by considerable efficacy in treating influenza A. n 18 cl, 8 dwg, 29 tbl, 13 ex |