| abstract |
FIELD: medicine. n SUBSTANCE: invention refers to medicine, namely to oncology, and concerns using a pharmaceutical combination for treating liposarcoma. Pharmaceutical combination contains (i) (S)-5-(5-chloro-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-6-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-1-isopropyl-5,6-dihydro-1H-pyrrolo[3,4-d]imidazol-4-one, or a pharmaceutically acceptable salt thereof, and (ii) 7-cyclopentyl-2-(5-piperazin-1-ylpyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide, or its pharmaceutically acceptable salt. n EFFECT: invention provides effective treatment of liposarcoma in a patient. n 9 cl, 3 dwg, 3 tbl, 3 ex |