http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2672874-C2

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filingDate 2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de757ed72c58b09e4674dec006bc50c2
publicationDate 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2672874-C2
titleOfInvention Methods and systems for identifying and treating anti-progestin sensitive tumours
abstract FIELD: medicine. n SUBSTANCE: group of inventions relates to medicine and can be used to suppress the growth of a tumour susceptible to growth inhibition by anti-progestins. To do this end, a sample of the patient's tissue, which presumably is oncogenic or cancerous, is obtained. Progesterone receptor-positive (PR-positive) cells are detected in the tissue sample. Degree of spread of progesterone receptor foci in the nuclei of progesterone-positive cells present in said tissue sample is determined. Onapristone antiprogestin is administered to the patient if there are clearly expressed progesterone receptor foci in said tissue sample that exceed 5 % of the number of PR-positive cells. Methods are also disclosed for treating a patient with a tumour susceptible to growth inhibition by anti-progestins, or who presumably has a tumour susceptible to growth inhibition by onapristone, and a system for classifying the tumour as susceptible to onapristone treatment. n EFFECT: group of inventions provides treatment of a patient with a tumour susceptible to growth inhibition by onapristone. n 17 cl, 11 tbl, 4 dwg, 6 dwg
priorityDate 2011-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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