http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2671510-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99cd2888b2026702c522c60b1544ff90 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06M11-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 |
| filingDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c9ac86b0782cefec7131c2f24bedd0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205cd792e998612fef53abb63a6e48e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a665dc159a7af035b439a5ef4c6c5a13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_919e263495390de904a545607d261030 |
| publicationDate | 2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2671510-C1 |
| titleOfInvention | Method of isolation of high-molecular protein activation complex of human caspase-2 |
| abstract | FIELD: medicine. n SUBSTANCE: proposed group of inventions relates to medicine. Methods for isolating a high molecular weight protein complex for the activation of human caspase-2, formed in cancer cells in response to DNA-damaging chemotherapeutic treatment, are proposed. Cancer cells are incubated in the presence of a DNA-damaging chemotherapeutic drug until the maximum level of caspase-2 activation is obtained. Cells are harvested, followed by addition of a lysis buffer, separation of the cell debris from the lysate containing the high-molecular caspase-2 activation complex, separation by gel filtration of the resulting cell lysate, with the separation of fractions containing high-molecular forms of caspase-2 from fractions containing its monomeric forms and isolation from the fraction containing high-molecular forms of caspase-2, a high-molecular protein complex of caspase-2 activation. n EFFECT: proposed group of inventions provides an effective isolation of the complex of activation of human caspase-2. n 36 cl, 5 tbl, 1 ex, 17 dwg |
| priorityDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.