http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2668828-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e74d0ffc957c5050ae3dbe1dec053f13 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 |
filingDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2bf56c9442a633cda509ce96f20fcf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_644e6f2573dc79ce9f93951141492a05 |
publicationDate | 2018-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2668828-C1 |
titleOfInvention | RECOMBINANT PLASMID DNA pPDGFB ENCODING A POLYPEPTIDE WITH HUMAN PLATELET-BB GROWTH FACTOR HUMAN PROPERTIES, AND A RECOMBINANT STRAIN OF METHYLOTROPHIC YEAST PICHIA PASTORIS, A PRODUCER OF A POLYPEPTIDE WITH HUMAN PLATELET-BB GROWTH FACTOR HUMAN PROPERTIES |
abstract | FIELD: biotechnology. n SUBSTANCE: present invention relates to biotechnology and in particular to genetic engineering and can be used in medical studies to obtain a human platelet growth factor. Recombinant plasmid DNA pPDGFB encoding the synthesis of a polypeptide with human platelet-BB growth factor, which provides biosynthesis with a level of about 40รท60 mg of recombinant protein/liter culture. Highly efficient synthesis of the target polypeptide is ensured by the fact that the target gene is under the control of the strong inducible promoter AOX1. n EFFECT: present Pichia pastoris strain GS115PDGFB provides the synthesis of a polypeptide with human platelet-BB growth factor in an amount of at least 40 mg of the target protein per liter of culture. n 2 cl, 4 dwg, 3 ex |
priorityDate | 2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.