http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2668514-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c07a4eb781ba7a1b508c870ffb447b6c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21068 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
| filingDate | 2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ec3e347a284e086fba2bec34fcb54ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee74b1292d0dcc8c26a5ee1ed3bf6a01 |
| publicationDate | 2018-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2668514-C2 |
| titleOfInvention | Steroidal nitrones for treatment and prevention of cerebral stroke or ischemia, alzheimer's and parkinson's disease and amyotrophic lateral sclerosis |
| abstract | FIELD: pharmacology. n SUBSTANCE: group of inventions relates to pharmacology and medicine. Disclosed are: the use of a steroidal nitrone selected from compounds (E)-N-((8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-7,8,9,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H,6H,10H)-ylidene)methanamine oxide (F2) and (Z)-N-((8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-7,8,9,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H,6H,10H)-ylidene)methanamine oxide (F3), or pharmaceutically acceptable salts and hydrates of said compounds for the manufacture of a pharmaceutical composition or a medicament for the prevention and / or treatment of stroke or cerebral ischemia, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis; the composition based thereon, having neuroprotective action, use of said composition in combination with a thrombolytic agent for the treatment of stroke or cerebral ischemia, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. n EFFECT: technical result consists in the neuroprotective, antioxidant action of said steroidal nitrones for which the blood-brain barrier is highly permeable. n 6 cl, 5 dwg, 1 tbl |
| priorityDate | 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 211.