Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da1e65323879f4dc504c2a3b50a210c6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-375 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
filingDate |
2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9518c66533bbd758f5888d8f54567af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bdfd994c9895610e1013c98851f4604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b7fe460eeace0a0a420c3a72c41bd1c |
publicationDate |
2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2665802-C2 |
titleOfInvention |
Fusion protein based on recombinant ganoderma immunoregulatory protein and human serum albumin, method for preparation thereof, as well as use thereof |
abstract |
FIELD: chemistry.SUBSTANCE: present invention relates to the field of biotechnology, specifically to the recombinant production of a fusion protein consisting of a ganoderma immunoregulatory protein and human serum albumin (HSA), and can be used in medicine to treat leukopenia and as an antitumour agent. Obtained is an rLZ-8-HSA fusion protein, in which the C-terminus of the ganoderma immunoregulatory protein is connected to human serum albumin via a binding peptide.EFFECT: invention improves the biological activity of rLZ-8-HSA ganoderma fusion protein and increases its in vivo half-life in comparison with rLZ-8.10 cl, 4 dwg, 7 tbl |
priorityDate |
2013-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |