| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to lupane and 2,3-seco-lupane C28 amides with fragment of 2-aminobutan-1-ol of general formula: n in which R 1 =(R)-(-)-2-butan-1-ol, or R 1 =(S)-(+)-2-butan-1-ol, or R 1 =(R,S)-(+/-)-2-butan-1-ol, or R 1 =(R)-(-)-2-butan-1-ol, or R 1 =(S)-(+)-2-butan-1-ol, or R 1 =(R,S)-(+/-)-2-butan-1-ol, or R 1 =(R)-(-)-2-butan-1-ol, or R 1 =(S)-(+)-2-butan-1-ol, or R 1 =(R,S)-(+/-)-2-butan-1-ol. n EFFECT: new chemical compounds of lupane triterpenoids class, exhibiting virus-inhibiting activity against herpes simplex virus type I (HSV-1), are obtained, and/or virucidal activity against herpes simplex virus type I (HSV-1) or against HIV-1. n 4 cl, 3 tbl, 13 ex n или - or |