http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2663899-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7fada561413fe96444fd3c6bfa206ec |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 |
filingDate | 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37240548d4808bf85910958541ae599b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e900d25bfcf67a18f61168c7f5d6b63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cded4e5741a96320194ba896502bdc55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_730796ee00fb4f6aa901eee8a036c11c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_646047d77f9f37976e48db6a1c79ce35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e48edf6f6918c61879699f593697e11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d66227f0870c9c76cc283c6bd0cbb2d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_232fba4bd35611764e2eadc89c8819a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8193f1b140bf0230a09c20e2c7c7a0fa |
publicationDate | 2018-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2663899-C1 |
titleOfInvention | Process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone |
abstract | FIELD: chemistry.SUBSTANCE: invention relates to pharmaceutical chemistry, in particular to a process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone (phenothropyl). Process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone (phenothropyl) is that the alkali salt of 4-phenyl-2-pyrrolidone is alkylated in toluene with 2-chloroacetamide, add cold water with the evolution of the resulting phenotropil, separate the aqueous and organic layers, the aqueous layer is extracted with toluene, the resulting extracts are combined with the toluene layer, and unreacted 4-phenyl-2-pyrrolidone is recovered, and further extraction of the aqueous layer with ethyl acetate yields an additional amount of phenothropyl.EFFECT: advantages of the method are the reduction of the process steps and the use of more accessible raw materials.1 cl |
priorityDate | 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.