http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2660364-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf38d6baa4a01b92d30add4c36855598 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate | 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd23d5aa8641da230d15b5268b717575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a01fb5f4b6c5439fe6d114ca912282d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d4755be5580c2e26c4450fa683ebae4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe33e76a8e05dc91716ca74e9f11e0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6cb17f56c2b42cad534252bfa460134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeb2f5c4fa24b8cec58cd2ea97d39730 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd00eae2745101f6f656f9b50fc815e4 |
| publicationDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2660364-C1 |
| titleOfInvention | Method for quantitative determination of lycarbazepine in blood plasma |
| abstract | FIELD: medicine. n SUBSTANCE: invention relates to medicine, namely to clinical pharmacology, and can be used for the quantitative determination of lycarbazepine in blood plasma for solving the problems of drug monitoring of the second generation anticonvulsant in the treatment of partial epilepsy. Method for the quantitative determination of lycarbazepine in blood plasma by performing liquid-liquid extraction of lycarbazepine from blood plasma followed by gas chromatography-mass spectrometry of extraction products and calculating the concentration of lycarbazepine includes extraction of the analyte and the internal standard, nordazepam, gas chromatography-mass spectrometry of a solution of extraction products comprising the analyte and an internal standard, followed by calculating the concentration of lycarbazepine according to formula: Y=6.710⋅X+0.7567, where Y is the concentration of lycarbazepine (mcg/ml), X is the ratio of the area of the chromatographic peak of lycarbazepine to peak area of the internal standard, nordazepam. n EFFECT: method for quantitative determination of lycarbazepine in blood plasma has been proposed. n 1 cl, 2 tbl, 3 dwg |
| priorityDate | 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.