| abstract |
FIELD: medicine. n SUBSTANCE: invention relates to the field of medicine, in particular to gynecology, and is intended to prevent menstrual disorder in patients. Level of vitamin D in the blood serum is determined. With its content < 16.2 ng/ml, DNA isolation and genotyping of genes are performed GC rs2282679, CYP2R1 rs2060793, VDR rs2228570. When genotypes are identified C/C VDR rs2228570 and/or A/C GC rs2282679 vitamin D at a dose of 4,000 U/day is prescribed. When genotypes are identified T/T VDR rs2228570, T/T CYP2R1 rs2060793 and A/A GC rs2282679 2,000 U/day for 9 months is prescribed. n EFFECT: invention provides a differential choice of the optimal dose of vitamin D. n 1 cl, 3 tbl, 3 ex |