http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2658824-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfd981147185ad108ff12d3648dae3d9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
| filingDate | 2014-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e3bdaae8c5dfc84ccb88f41e1bec99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf9ed9b772af94456a31854f9af298b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3aa2a692b9f75c00ee3d16c37121e6b |
| publicationDate | 2018-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2658824-C2 |
| titleOfInvention | S-crystal form of ivabradine hydrochloride, preparation method and pharmaceutical composition thereof |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to a novel S-crystalline form of ivabradine hydrochloride, a process for its preparation, and a pharmaceutical composition thereof. S-crystalline form of ivabradine hydrochloride has an X-ray powder diffraction pattern having characteristic peaks at positions expressed in 2-theta degrees: 8.5±0.2, 11.5±0.2, 14.6±0.2, 15.3±0.2, 16.1±0.2, 17.1±0.2, 17.5±0.2, 17.8±0.2, 18.6±0.2, 19.3±0.2, 21.6±0.2, 21.9±0.2, 27.2±0.2, and, according to DSC, has an endothermic peak of crystalline transformation as a characteristic peak at 111.6°C, and an exothermic crystalline transformation peak as a characteristic peak at 136.9°C, and a melting decomposition peak as a characteristic peak at 194.9°C. n EFFECT: products based on the S-crystalline form are easy to dry, have high purity and stability, and are convenient for long-term storage, without special requirements for temperature and humidity. n 8 cl, 5 tbl, 7 ex |
| priorityDate | 2014-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.