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filingDate 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3adeb69f5c8ea77b6c22a109ecf17d57
publicationDate 2018-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2657419-C1
titleOfInvention Pharmaceutical composition for national administration
abstract FIELD: medicine; pharmaceuticals. n SUBSTANCE: pharmaceutical composition for nasal administration comprises a complex of active components based on diphenhydramine hydrochloride, zinc sulfate and a water-soluble vasoconstrictor and a complex of auxiliary components comprising an isotonic agent, pH adjusting agent, a pharmaceutically acceptable gelling agent, a quaternary ammonium compound preservative and distilled water in the amounts indicated in the claims. As a vasoconstrictor, the composition comprises xylometazoline hydrochloride or phenylephrine hydrochloride. As a gelling agent, it contains carboxymethylcellulose or hydroxypropylmethylcellulose. As a preservative, the composition contains benzalkonium chloride or dodecyldimethylbenzylammonium chloride. As an isotonic agent, it contains sodium chloride or sodium hydrogencarbonate. As an agent regulating the pH of the aqueous phase, it contains sodium citrate, citric acid or sodium hydrochloride. n EFFECT: composition of the invention is characterized by high therapeutic efficacy and accelerates the epithelialization process of the nasal mucosa. n 8 cl, 4 ex
priorityDate 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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