http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2654673-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a29888b26633bf51e09ca2b0d6c3bcb8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15034 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-155 |
| filingDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a57610c05cc22739a22908212ec8c655 |
| publicationDate | 2018-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2654673-C2 |
| titleOfInvention | Mutated lentiviral env proteins and their use as drugs |
| abstract | FIELD: biotechnology. n SUBSTANCE: proposed group of inventions relates to biotechnology. Disclosed is a composition which induces increased immune response against lentivirus, and its use for the prevention or treatment of lentiviral infection, and also a method for preparing the active substance of the disclosed composition. Disclosed composition contains, as an active substance, an isolated mutated lentiviral ENV protein of a human or monkey, substantially devoid of immunosuppressive activity, or a fragment thereof. Said protein or fragment comprises a mutated immunosuppressive domain (ISU), comprising the amino acid sequence SEQ ID NO: 416 and providing no immunosuppressive activity of said ENV protein or fragment, while maintaining their antigenicity, three-dimensional structure and their expression on a plasma membrane. n EFFECT: present composition can be used in medicine to prevent or treat lentiviral infection. n 16 cl, 7 dwg, 16 tbl, 2 ex |
| priorityDate | 2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 264.