http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2652567-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97601b09535997694d4b6c9263693974 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0023 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 |
| filingDate | 2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c890fda28fdc3eb669c01d4e3e9ed02b |
| publicationDate | 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2652567-C1 |
| titleOfInvention | Microneedic applicator and method of its manufacture |
| abstract | FIELD: medicine. n SUBSTANCE: group of inventions relates to injection devices. Microneedic aplicator comprises a microneedic template containing more than one micro-needles, made biodegradable and carrying a drug, and a substrate. Microneedles of the matrix consist of two parts, the first part that faces the point of the microneedle is 60–95 % of the microneedle height and is made from a mixture of a carrier biodegradable agent and a drug, second part, making up the remaining height of the microneedle to the base of the microneedle, is made of a biodegradable component, as a substrate, the microneedic applicator comprises a layer made of a biodegradable component or an insoluble agent, ratio of the specific dissolution rates of a carrier biodegradable agent and a biodegradable component is 1:200,000÷950,000 respectively. In the manufacture of a microneedic applicator, microneedles of a micro needle matrix are made in two parts height long, to form the first part, a mixture of a carrier bioresorbable agent and a drug is placed in the cone-shaped mold cavities to a height of 60–95 % of these wells height, mixture is kept at a negative pressure and dehydration process is carried out at a temperature of +22÷90 °C for 8÷72 hours; to form the second part, the remaining volume of the wells is filled with a biodegradable component, also it is held at negative pressure, then the process of dehydration is carried out at a temperature of +22÷90 °C for 8÷72 hours, a substrate is placed above the wells. n EFFECT: group of inventions allows to reduce the reaction to a foreign body, to control the release time of a drug. n 22 cl, 2 dwg, 1 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11318292-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3826708-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112218675-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2804809-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019231360-A3 |
| priorityDate | 2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.