abstract |
FIELD: biotechnology. n SUBSTANCE: invention relates to biotechnology, specifically to an artificial nucleic acid molecule. Synergetic effect provided by the presence of 3'-UTR of an albumin gene and the 3-untranslated region of the mRNA, placed in the secondary stem-loop sequence, in the structure of the artificial nucleic acid sequence, allows to increase the stability and prolong the expression of the encoded protein. n EFFECT: invention further relates to the use of such an artificial nucleic acid molecule, encoding therapeutic peptides or proteins in medicine for gene therapy and/or genetic vaccination. n 63 cl, 23 dwg, 5 ex, 14 tbl |