| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5205c25b782ff85e96fda9512faca381 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 |
| filingDate |
2016-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2675347dba3390abaf82f5aa8ebefaf1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_770c2e4869630fd93452c1f78793e7e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0e4fc09838ce391b13242f0436d1c8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d282e10d26ffb170cbcfeee308c2d0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bb1ba7771f2a09bad34c8089f8bd8d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b04dd9ab35724d7f2b122bd122b3b07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_820e7d23e00d0cffa5cd866ece0e39c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40fbd8b76e831672dba33cc551b394d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e93b3aae0052a2c259112da82c15591d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4034185c83d29d49dff3f0038b6ab3bc |
| publicationDate |
2018-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2643671-C1 |
| titleOfInvention |
Method for retinal ischemia-reperfusion prevention by minoxidil in experiment |
| abstract |
FIELD: medicine. n SUBSTANCE: method involves preliminary preconditioning by the drug via single intragastric administration of its solution to a laboratory animal. Subsequent modeling of retinal ischemia is carried out by mechanical pressure of 110 mm Hg on the anterior chamber of the eye for 30 minutes. Minoxidil in an amount of 0.5 mg/kg of animal body weight is used as a drug 60 minutes before simulation. The retinoprotective effect of minoxidil is assessed by electro-retinography after 72 hours of reperfusion. n EFFECT: pronounced correction of retinal ischemia-reperfusion in the experiment, which is confirmed by achievement of retinal microcirculation levels and restoration of the electrophysiological activity of the retina. n 1 ex, 2 tbl |
| priorityDate |
2016-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |