http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2642924-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1a4c87205c91b269da1d82891e438a9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-38 |
| filingDate | 2017-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac81e3584a3173a886ca79e0eebad82c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d7c55bb134bbacfbd2f5b01c673ffaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e246f7f6af9a0a44710f9ddf7dadcc04 |
| publicationDate | 2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2642924-C1 |
| titleOfInvention | Method of producing 5-phenyl-3- (trifluoromethyl) -1n-pyrazole-4-amine |
| abstract | FIELD: chemistry. n SUBSTANCE: method of producing 5-phenyl-3-(trifluoromethyl)-1N-pyrazole-4-amine, which has the formula given below. This compound is the key in the synthesis of hybrid molecules that have different types of biological activity. The essence of the method is that 4,4,4-trifluoro-1-fenilbutadionate of lithium is treated with sodium nitrite in glacial acetic acid under cooling, and then with the excess of hydrazine hydrate. In this case, acetic acid is used as the organic solvent. n EFFECT: method allows to process in a single reactor, without isolation of intermediates, without the use of high or low pressure, at a temperature of 10 to 20 degrees, which leads to increase of the selectivity of the process, reduction of the number of operations when selecting the target compounds and provides the target compound with a yield of 93%. n 1 ex |
| priorityDate | 2017-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.