http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2641285-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d9eccbd3fb5bc9127faabec00152075 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 |
| filingDate | 2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4c0e2cdf5385a293e926f0f5b3da9c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afdd78b981c6cffdea38cdcba0c3c640 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79a385c34185cf82695bab404a2a545c |
| publicationDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2641285-C2 |
| titleOfInvention | Quinine compounds, method for their production and their medical application |
| abstract | FIELD: pharmacology. n SUBSTANCE: invention relates to a compound of formula I n n n n or a pharmaceutically acceptable salt or optical isomer thereof, wherein, in formula I, n is selected from 1 to 7, R 1 means C 3 -C 7 hydrocarbyl, which may be unsubstituted or optionally substituted by halogen, alkoxy, alkoxycarbonyl, heterocyclyl or aryl; R 2 is aryl or heteroaryl containing one or more heteroatoms selected from N, O or S which may be unsubstituted or optionally substituted by one or more substituents of halogen, phenyl, -OR 6 , -SR 6 , -NR 6 R 7 , -NHCOR 6 , -CONR 6 R 7 , -CN, -NO 2 , -COOR 6 , -CF 3 or linear or branched C 1 -C 4 hydrocarbyl, R 6 and R 7 can denote a hydrogen atom or linear or branched C 1 -C 4 hydrocarbyl; R 3 is hydroxyl, halogen, alkoxy or acyloxy. Alkoxy or acyloxy may be unsubstituted or optionally substituted by halogen, hydroxyl, alkoxy, hydrocarbyl, alkoxyhydrocarbyl, heterocyclyl or aryl; R 4 and R 5 may or may not be present, and, independently, can mean, without limitation, a substituent such as halogen, hydroxyl, alkoxy, hydrocarbyl, alkoxyhydrocarbyl, heterocyclyl or aryl when these radicals are present. Y is linear or branched C 1 -C 7 alkyl or - (CH 2 -O-CH 2 ) m -, which may be optionally substituted by halogen, hydroxyl, alkoxy, alkoxyalkyl, unsaturated hydrocarbyl, cyclic hydrocarbyl or heterocyclyl. M is 1-3; X - means an acid residue or hydroxyl, the said compounds having a selective antagonistic effect on the M 1 and M 3 receptors subtypes, but insignificantly affect the M 2 receptor subtype. n EFFECT: compound application efficiency increase. n 24 cl, 5 tbl, 33 ex |
| priorityDate | 2013-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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