| abstract |
FIELD: pharmacology. n SUBSTANCE: invention relates to application of 5-aminoimidazole-4-carboxamidiborofuranoside (AICAR) as a geroprotector in a nutrient medium for model animals. In case of nematodes, the geroprotective effect of AICAR is achieved in concentrations of 0.05 mM and 0.1 mM. In case of drosophila flies, the geroprotective effect of AICAR is achieved in concentrations of 0.5 mM and 1.0 mM. n EFFECT: increased life expectancy of model animals. n 3 cl, 5 dwg, 3 ex |