http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2638787-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0289b5c7b14585b669edc2580623cb4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 |
filingDate | 2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b31254299085680bdcadab55d708fb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_407b2c757dd5a07ab05ea779a74bd1df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d24a687a6b8cfdb6ad54a9a98e9e585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2231a3b3b991747fdb99855f68ebda0a |
publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2638787-C1 |
titleOfInvention | Method for obtaining of analytical test system based on suspension microchips for diseases markers detection |
abstract | FIELD: medicine. n SUBSTANCE: suspension microchips are created by optical coding of microspheres of various diameters with fluorescent dyes with their subsequent conjugation with biological recognition molecules. Detecting components are created by conjugating biological detection molecules with fluorescent dyes. For optical coding of microspheres of different diameters, semiconductor fluorescent nanocrystals are used, which are layered on the surface of microspheres. At that, a layer of semiconductor fluorescent nanocrystals of the same colour is spatially separated from the adjacent layer of semiconductor fluorescent nanocrystals of a different colour by three or more layers of polyelectrolytes. To form the outer layer of polyelectrolyte, a polymer is used that includes functional groups for specific and/or oriented conjugation of biological recognition molecules. To label the biological detection molecules, fluorescent dyes excited at one wavelength with the applied semiconductor fluorescent nanocrystals are used. n EFFECT: invention allows creation of test systems that allow detection and quantification of a variety of different protein markers, for example, oncological diseases of female reproductive system, using flow cytometry on standard flow cytometers. n 22 cl, 3 dwg |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2701742-C1 |
priorityDate | 2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.