http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2636049-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f11390a0601d6520c1d8695c6a4f6744 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 |
filingDate | 2013-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dd25d7a0beb06ef8f9a68a294eaf785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411dfa9c7aec99babd66dc22dc027b93 |
publicationDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2636049-C2 |
titleOfInvention | Method of producing igg composition by thermal processing |
abstract | FIELD: chemistry. n SUBSTANCE: method comprises the following steps: (a) diafiltration of the partially purified IgG solution to achieve an ethanol concentration of less than 0.5% (w/v); b) stabilization of the solution produced in step a) using sorbitol as a stabilizing agent at a sorbitol concentration of between 30 wt % and 35 wt %; c) heat treatment of the solution produced in step b) at a temperature between 55°C and 63°C for a period of time between 1 and 24 hours; d) selective adsorbtion of aggregates and/or high molecular weight polymers from the solution subjected to the heat treatment in step c) by cation chromatography; and e) diafiltration and preparation of the solution produced in step d). n EFFECT: invention provides stability of the final product. n 27 cl, 22 tbl, 18 ex |
priorityDate | 2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.