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publicationDate 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2634395-C1
titleOfInvention GENETIC CONSTRUCT BASED ON CRISPR/Cas9 GENOME SYSTEM EDITING, CODING Cas9 NUCLEASE, SPECIFICALLY IMPORTED IN HUMAN CELLS MITOCHONDRIA
abstract FIELD: biotechnology. n SUBSTANCE: genetic construct of pMitoCas9 with SEQ ID NO:1 based on the CRISPR/Cas9 genome editing system is obtained, which encodes the cas9 nuclease, specifically imported into human mitochondria. n EFFECT: invention provides efficient synthesis of modified Cas9 nuclease in human cells. n 2 dwg
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