http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2634351-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f9031dad28e33b2174c8933e0141c7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-12 |
| filingDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1133885dc542504bb9cba90e22c3e4e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690d86f2de1344cfeb4c5164cb949df1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab256070645f845290fef25b2ebcaaa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea3598874a0d54e68152ee0c82e5fd47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_463b8d9ce134f4133d21edc71b98aaca |
| publicationDate | 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2634351-C1 |
| titleOfInvention | Method for producing 2-aryl(hetaril)-7-methyl-1,2,3,4-tetrahydropyrido[3',2':4,5]tiene[3,2-d]pyrimidine-4-one derivatives |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to the synthesis of substituted 1,2,3,4-tetrahydropyrido[3',2':4,5]thiene[3,2-d]pyrimidine-4-ones of general formula 1, including the reaction between 3-amino -6-methylthieno[2,3-b]pyridine-2-carboxamides 2a, b and aromatic aldehydes 3a, b or 3-(4-methoxyphenyl')-pyrazole-4-carbaldehyde 3b, the tetrahydropyrimidinone ring according to the invention is formed by boiling the reagents in acetic acid, which is used simultaneously as an acid catalyst and solvent for 4.5-6 hours in the molar ratio of reactants of 2: 3 and the acetic acid ratio of 1:1.1:77.3, respectively: n n n n 1a:R 1 =Me, R 2 =o-C 6 H 4 NO 2 ; 1b:R 1 =CH 2 OMe, n n n n 1c:R 1 =CH 2 OMe, R 2 =C 6 H 2 (OMe) 3 (2,3,4). n EFFECT: increasing the selectivity, decreasing the reaction time and increasing the yields of target products. n 1 tbl, 7 ex |
| priorityDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.