http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2633507-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efd706127ac97d30a769021f67bff3d4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9071fe5438e6d9ac3f9b24de622880b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b293bacbeb0d34f2f7e574adcaf38d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f8884251af7dd1b893ae5e17fb873b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df3f8dbfec5baaf9e74c914383ccc841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7214c88d68bfbe6a71b1c2a2edc1b9a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84d68418a7a2a4bff341f253e54de139 |
| publicationDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2633507-C2 |
| titleOfInvention | Method for molecular-genetic detection of tuberculosis microbacteria resistance to antitubercular preparations of second series (fluoroquinolones, aminoglycosides and capreomicin) |
| abstract | FIELD: biotechnology. n SUBSTANCE: method for determination of mycobacteria tuberculosis resistance to antitubercular preparations of the second series - fluoroquinolones, aminoglycosides and capreomicin, sets of detection probes and amplification primers and method for confirmation of the clinical diagnosis of extensively drug-resistant tuberculosis. The method involves simultaneous detection of mutations in the tuberculosis mycobacteria DNA in a biological sample, leading to microorganisms resistance to antitubercular preparation of the second series in the sites of gyrA gene (codons 89, 90, 91, 94), gyrB gene (538, 539, 540), rrs gene (positions 1401, 514, 517) and the eis promoter region (positions -10, -12, -37), by real-time MPCR using primers for amplification and detection probes complementary to these gene sites. n EFFECT: simultaneous and rapid determination of tuberculosis mycobacteriua resistance to second-series preparations, and can be used in the diagnosis of extensively drug-resistant tuberculosis. n 11 cl, 5 tbl, 3 ex |
| priorityDate | 2015-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.