| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ede59ba89e22869ac36d7e6ce19e00f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-07 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9802464fe3015db856b0cf714f059bfa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e746062abc2da636e74aef46da8531e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_140d2073b8174cc5505c89e231e3e4f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b4dfaefd625a8fe9132ba53868926f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dedb590ab22e840c3972c7f54145233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2320a763f2b29f412730b4a8071428af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fee48f6139ee214944b72a6440b98fef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fee5df47b87176fad972002fa1b7650f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3256a5ba8b005b3f60c858150db2f7af |
| publicationDate |
2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2633504-C1 |
| titleOfInvention |
Ecoli strain - producer of full-dimensional protective bacillus anthracis antigen in form of virus-like particles |
| abstract |
FIELD: biotechnology. n SUBSTANCE: presented strain was derived from the protective Bacillus anthracis antigen by inserting the pGEM-TTPPAG plasmids into the E. coli strain BL21 (DE3). The plasmid pGEM-TTPPAG contains a T7 phage promoter that controls the expression of a fusion gene that is a full-length TTR bacteriophage DT57C gene (encodes the pb6 tail tube protein) fused at the 3'-end with the B. anthracis protective antigen gene and expressed in the form of virus-like particles. The obtained HPV, free of soluble cell protein, can be used as an antigen for immunization. n EFFECT: increasing the yield of the target product under optimal cultivation conditions, obtaining the main protective antigen of the causative agent of the anthrax in the form of virus-like particles, which facilitates its purification and potentially increases immunogenicity. n 5 dwg, 3 tbl |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2761637-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2789418-C1 |
| priorityDate |
2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |