http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2632003-C1

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filingDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e10493c0a63536e3613545aaddf2e7
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publicationDate 2017-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2632003-C1
titleOfInvention Method of producing 2,2-pentamethylene-4-oxo-2,2,4,5,6,6-hexahydro-1h-cyclopenta [d] pyrimidine
abstract FIELD: chemistry. n SUBSTANCE: invention relates to an improved method of producing 1',5',6',7'-tetrahydrospiro [cyclohexane-1,2'-[2H] cyclopentapyrimidine]-4'(3'H)-one, which can be used for synthesis of biologically active compounds, in particular a medicinal substance of ipidacrin, capable of regulating neuromuscular transmission. The method consists in condensing cyclohexanone in a solvent with adiponitrile according to the following scheme: . The condensation is carried out by successive adding adiponitrile and then cyclohexanone to the solution of sodium tert-butylate in toluene, followed by isolation of the final product. n EFFECT: output is increased, the quantity of waste is reduced, and the time of the process is shortened. n 3 ex
priorityDate 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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