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filingDate 2016-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a2cd6e4311a98cae04dddd3e4ae3712
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publicationDate 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2631792-C2
titleOfInvention Method for obtaining of mature antigen-activated dendritic cells with transfection of tumour cells rna of breast cancer
abstract FIELD: biotechnology. n SUBSTANCE: invention relates to a method for obtaining of mature antigen-activated dendritic cells (DC) by transfection of the breast cancer tumour cells RNA, and can be used in medicine. Mature antigen-activated DCs are obtained through a combination of magnetic transfection of breast cancer tumour cells RNA at a ratio of 0.3 μg RNA to 0.3 μl of suspended magnetic particles with a stimulator of maturation at a dose of 25 ng/ml for 24 hours. n EFFECT: invention allows effective stimulation an antitumour cytotoxic immune response against breast cancer cells. n 1 tbl, 1 ex
priorityDate 2016-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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