| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to methods of synthesis of an imaging agent having a formula presented below, and its precursors. In said formula R 1 denotes alkyl; R 2 denotes hydrogen or halogen; W is -O-CH 2 ; R 3 is alkyl substituted with 18 F isotope, alkoxyl substituted with 18 F isotope, or alkoxyalkyl, substituted with 18 F isotope, and n is equal to 1. Methods can ensure high output and large-scale synthesis in automated systems of imaging agents containing radioisotope 18 F, which can be used as sensors, diagnostic tools, including for assessing blood supply, including myocardial blood supply. n EFFECT: methods can ensure high output and large-scale synthesis in automated systems of imaging agents containing radioisotope 18 F, which can be used as sensors, diagnostic tools, including for assessing blood supply, including myocardial blood supply. n 16 cl, 13 dwg, 21 tbl, 49 ex |