abstract |
FIELD: biotechnology. n SUBSTANCE: recombinant yeast of the strain Kluyveromyces lactis DSM 25405, Kluyveromyces lactis DSM 25406 or Kluyveromyces lactis DSM 25407, which carry the gene for VP2 antigen of the infectious bursitis virus (IBDV), integrated into the yeast genome and providing the expression of the VP2 antigen of IBDV as a foreign protein. A method of subcutaneous vaccination with whole yeast cells of these recombinant yeasts is presented. n EFFECT: group of inventions makes it possible to make the method of subcutaneous vaccination more economical, provides effective protection in viral infections as a result of subcutaneous vaccination using much smaller amounts of yeast. n 17 cl, 13 dwg, 1 tbl, 9 ex |